DNA Repair Database

Term: 
2018-2019 Summer
Faculty Department of Project Supervisor: 
Faculty of Engineering and Natural Sciences
Number of Students: 
4

DNA Repair is an important mechanism to keep the genome integrity. There have been recent studies on DNA repair with the aim of understanding how DNA repair is regulated genome-wide. To understand genome-wide repair events, Next-Generation Sequencing technologies were developed: XR-seq and Damage-seq. Although the datasets were published, it is challenging for nonspecialists to retrieve datasets released in an unorganized fashion. Also, because computational processing needs a profession, it is not straightforward for a regular user to benefit from the raw data. Processed data files can be useful for "ready consumption" for researchers. This project aims to develop a database to host and serve raw and processed DNA Damage and Repair datasets along with available epigenomic data sets for cell lines and tissues.

Related Areas of Project: 
Computer Science and Engineering
Molecular Biology, Genetics and Bioengineering