Double Tail Surfactants Synthesis for Nano-Lipids Formation and Potential Application for Vaccine Formulation

In this project we are planning to design and synthesis of Gemini (double tail) surfactants for nano-lipids formation and mRNA encapsulation. In this purpose we are planning to synthesize four different thype double tail surfactants (nonionic, anionic, cationic and zwitterionic) and characterize their chemical structure and functionality by FT-IR and two-phase titration. Than  comparison of their micelles formation will be studied by using dynamic light scattering method. 
Students will learn how to synthesize and characterize  surfactants, and micelles formation for mRNA encapsulation. The project open only for Material Science, Bioengineering, Chemistry and Chemical engineering students. Candidates should have chemistry Laboratory experiences. Project open for only max 2-3 participants.