Comparative Preliminary Trial for DNA Retention Capacity of MXene and Silica-Embedded Filter Paper

Extracting nucleic acids from liquid samples is a critical step in molecular biology and diagnostics. Traditionally, silica-based methods and filter paper have been employed for their simplicity and cost-effectiveness. However, the emerging material MXene, a class of 2D transition metal carbides and nitrides, shows promise due to its unique surface chemistry, high adsorption capacity, and conductivity.
This study compares the efficiency of MXene-embedded filter paper and silica-embedded filter paper in extracting DNA from liquid samples with diminishing concentrations. The results will provide insights into the feasibility of MXene as an alternative or complementary tool for nucleic acid extraction in resource-limited settings. The objectives are to evaluate the efficiency of MXene in extracting DNA from liquid samples, compare the performance of MXene-embedded filter paper with silica-embedded filter paper, and assess the retention and purity of nucleic acids across a range of diminishing concentrations.